People across the world are observing Hemophilia day to create awareness about this fatal disease. Hemophilia is a rare disorder in which your blood doesn’t clot normally because it lacks sufficient blood-clotting proteins (clotting factors). The greater health concern is deep bleeding inside your body, especially in your knees, ankles and elbows. That internal bleeding can damage your organs and tissues, and may be life-threatening.
Signs and symptoms of hemophilia vary, depending on your level of clotting factors. Signs and symptoms of spontaneous bleeding include:
Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work
Many large or deep bruises
Unusual bleeding after vaccinations
Pain, swelling or tightness in your joints
Blood in your urine or stool
Nosebleeds without a known cause
There are several types of hemophilia, and most forms are inherited. However, about 30 percent of people with hemophilia have no family history of the disorder. In these people, an unexpected change (spontaneous mutation) occurs in one of the genes associated with hemophilia. The biggest risk factor for hemophilia is to have family members who also have the disorder.
Hemophilia is a genetic (inherited) disease and cannot be prevented. Genetic counseling, identification of carriers through molecular genetic testing, and prenatal diagnosis are available to help individuals understand their risk of having a child with hemophilia.